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Actovegin in US has been a controversial subject since news about sport celebrity doctor who used Actovegin on his high profile patients broke out more than 10 years ago. In fact Actovegin has been controversial in other countries as well, it was found with the cyclist legend Lance Armstrong which spurred up some big news storm and temporary action from doping regulators. Currently Actovegin is allowed by World Doping Agency and some consider it as legal doping.
Actovegin is a cocktail of amino acids, amino acids are the building blocks of proteins in our bodies. Actovegin is made from calfs blood. Sounds disgusting, right? But in reality by the time that blood is processed in to Actovegin tablet or made into injection it is far away from being blood. This is because in order for it to be effective medicine and safe for using it goes thru many repetitions of filtering out all the unnecessary stuff.
As I mentioned before Actovegin is full of amino acids, amino acids are a important part of our metabolism, the most known are glutamate, proline, glycine, taurine, leucine, alanine. Maybe you already recognized some of them , that is because they are often synthesized separately and sold in United States as performance enhancers. They often are praised for their health benefits. Actovegin is full of other useful substances like lipids, antioxidants, microelements and electrolytes. This unique natural cocktail has many health benefits and huge potential in treatment of various conditions.
Since Actovegin is mainly sold in Eastern Europe and Russia, one could think that it is manufatured by some small shady company in Russian woods. But it cant be further from truth, Actovegin is manufactured by large pharmaceutical company called ‘’Takeda’’ They are working in over 80 countries and regions worldwide, and 50% of their business is conducted in United States. Their revenue in year 2021 was 2,2 billion US dollars. Takeda makes medication in fields of oncology, rare diseases, neuroscience, gastroenterology as well as vaccines. All this coupled with 240 years of experience in medical field, means that one can convincingly say that Takeda is respected company world wide and manufactures high purity products including Actovegin. If you wish to learn more about company behind Actovegin, you can read more about it HERE.
Although Actovegin is a high quality product which has been sold for many decades in several countries, Actovegin in US is not sold locally. But Actovegin in US can be bought online. The reason for Actovegin not being sold locally in United States is unfortunate, it is financials. The cost of bringing new medical product to United States market is huge and company should be convinced that putting large amounts of money in that endeavour will pay off. Actovegin is a very interesting drug with many applications but the potential customer base is not big enough for Takeda pursue licensing. The licensing and getting product in the US market can cost anywhere between tens of millions to few billion US dollars
The fact that Actovegin is not sold locally in United States does not mean that is poor quality or don’t work, it simply means that the company behind it does not see the point of spending absurdly large amounts of money for US licensing.
In fact it is possible to buy Actovegin in US from online vendors. Because Actovegin is freely accessible in Eastern Europe, it is quite easy to buy it online with reliable shipping.to US. The only advice would be to buy Actovegin from a shop who offers PayPal this indicates that they are committed to getting the products to you or in the worst case ,they are forced to refund the money by PayPal .
Actovegin is used for wide range of conditions. Perhaps the most notable use for it is in sports medicine. Not surprisingly Actovegin in US is relatively popular choice for muscle recovery after injuries or workouts. This usage is not purely based on doctors and patients experiences, there are several studies which show the positive impact on muscle tears and recovery. One study described that recovery time of muscle injury decreased from 8 weeks to 5 weeks, which is a notable time reduction and any athlete would be happy to recover faster.
Even though there is many researches about Actovegin, currently scientist has yet to pinpoint the active compound of Actovegin. But the information in scientific literature clearly shows that Actovegin has antioxidant and cell death prevention properties, it may also upregulate responses responsible for muscle repair.
That’s all being said, Actovegin is used in variety of conditions and situations:
The most popular form of Actovegin is Actovegin tablets or often called pills. Online merchants report that this is the most popular Actovegin type in US as well.
Each tablet contains: deproteinized hemoderivative of calf blood – 200mg.
Each tablets has fillers: povidone K90, magnesium stearate, cellulose and talc
Coating is made from : , titanium dioxide ,mountain glycol wax , hypromellose phthalate, sucrose, acacia gum, diethyl phthalate -, dye quinolone, yellow minium varnish, macrogol and talc.
The instructions for use for Actovegin tablets:
Dosage: 1-2 tablets before meal 3 times/day. Course duration: 4-6 weeks. Can be repeated after 1.5-3 months break
As I noted before , the precise working principle of Actovegin is not clear but there have been many studies done to try understand how Actovegin does its magic. These studies have resulted in several findings.
One of the early studies in 1999 showed that Actovegin helps with transport and utilisation of glucose and oxygen, improves energy metabolism which leads to improved state of central nervous system. In fewer words – they found that Actovegin improves energy metabolism which means that Actovegin can be used as performance enhancing drug.
Other scientists did show that our cell powerhouses – mitochondria are positively impacted by Actovegin, their efficiency is enhanced. And even more this process depends on Actovegin concentration in the blood.These findings were observed in muscle mitochondria, these cells were able to burn more oxygen faster after Actovegin was introduced to blood stream. This translated to better sports performance and decreased recovery times.
We may not know what exactly is going on when Actovegin enters our blood stream or even what are the active substances of Actovegin but we know that Actovegin positively impacts energy metabolism and muscle chemistry which leads to better performance in sports and opens doors to treatment of many illnesses and conditions. Sadly Actovegin in US is not researched but my belief is that US researchers will cath up with time.
